Unexplained itching can sometimes accompany jaundice.

When bile flow is obstructed, substances normally processed through the bile system can accumulate in the bloodstream and contribute to itching.

But itching is also common with dry skin, allergies, medications, eczema, liver disease, kidney disease, and many other conditions.

If widespread itching appears suddenly and is accompanied by yellowing of the skin or eyes, dark urine, or pale stools, medical evaluation is recommended.

Why Early Symptoms Are Easy to Miss

One reason pancreatic cancer can be difficult to identify early is that its symptoms can overlap with everyday health problems.

For example, someone experiencing indigestion might assume they ate something that did not agree with them. Someone losing weight might believe that stress is responsible. Back pain may be blamed on sleeping in an uncomfortable position.